Investigation and technology have helped to develop the only product, worldwide, that eliminates hemorrhoids without the painful side effects of surgery. 

Its name is anuice®, and it’s the first product that eliminates hemorrhoids without the pain and the dramatic side effects of surgery, and in the comfort of your own home.

anuice®’s therapeutic action develops itself through the application of extreme low temperatures, applied in controlled manner, directly, by the patient; it’s what we know by the name of cryotherapy.

Cryotherapy with nitrogen and other chemical substances has been used for some years now in surgical procedures to treat different diseases, hemorrhoids among them; however, these procedures have the same painful effects of surgeries and hemorrhoidectomies. 

Through its cryogenic applicator, anuice® allows to take advantage of the same principles of cryotherapy, free of painful side effects, and with immediate, maintained through time, great results.

anuice®’s innovative applicator is made of neutral clinical plastic; this material, besides being an excellent transmitter of temperature, is modern and has important advantages, both clinical and technical. Some of those advantages are: it eliminates static, making impossible for particles and contaminating and allergenic agents to adhere to the surface of the device; the material also acts as a catalyst for the extreme low temperatures generated inside the applicator, which helps performing more effectively on the tissue that has been affected by the hemorrhoids. The nature of the plastic the device is made of also helps preventing irritation and burning due to extreme cold.

anuice®’s applicator anatomical design allows the device to adjust to the different areas of the affected parts; therefore, the device can be used in the treatment of internal and external hemorrhoids.

The refrigerable substance contained in anuice®’s applicator is responsible for the device to acquire the ideal temperature to produce the cryo-coagulation effect on the affected tissues and, by doing this, stimulate sanguine microcirculation in all the venous area of the anus and the rectum. This is achieved by leaving the device in the freezer, at least two hours before each application.

From the first application, the action of the extreme low temperatures, and its analgesic effects, vasoconstriction and anti-swelling eliminate all the symptoms, like pain, itching, burning, swelling and bleeding, which makes it easier for the patient to perform their daily activities without indisposition and immediately.  

2 to 3 applications per day, during four weeks, will allow the anus’ and the rectum’s varicose veins to regain the dynamic of the sanguine microcirculation, eliminating the hemorrhoids, and not permitting its reappearance.

anuice® does not contain chemicals, drugs, nor other active substances that may be absorbed by the user’s organism. This makes anuice® the ideal choice for all patients: older people, pregnant women, mothers who breastfeed, diabetics and users allergic to any substance.

Is the application of cold to the skin, causing local tissue destruction in an efficient and controlled.

At the cellular level causes cell membrane rupture, denaturation of lipoproteins and metabolic disorders. At vascular causes vasoconstriction followed by vasodilation, endothelial alterations, increased capillary permeability and thrombus formation, ischemia and tissue necrosis.

Clinically, it causes a sequential fashion:

• Nettle rash for histamine release.

• Edema, maximum at 12 to 24 hours.

• Vesiculation appears serous and hemorrhagic blister at 12 to 24

hours usually break after 48 hours without scarring.

• Crusting.

• Cell regeneration adversely affecting the melanocytes, which explains the residual risk of hypopigmentation in dark skinned individuals.

Most cell destruction occurs when the tissue frozen quickly and thawed slowly.

Treatment of choice in:

• Warts Vulgaris

• Flat warts

• Seborrheic warts

• Internal and external hemorrhoids

• Papilloma plantar

• Molluscum contagiosum

• Actinic keratosis

• Senile Lentigo

• Acrochordon

Bibliographic: Gibbs S., Harvey I., Sterling J., Stark R. Local treatments for cutaneous warts: systematic review. BMJ. 2002; 325 (7362): 461.